Lisinopril is a prescription medication used to treat high blood pressure and heart failure. It belongs to a class of drugs called angiotensin-converting enzyme (ACE) inhibitors. This medication helps to relax blood vessels and improve blood flow, reducing the workload on the heart. Lisinopril is also used to improve survival after a heart attack.
Important Safety Information: You should not take Lisinopril if you are allergic to it or any other ACE inhibitor. Inform your doctor if you have any medical conditions, including kidney disease, liver disease, diabetes, or a history of allergic reactions. Lisinopril may cause dizziness or lightheadedness, so avoid driving or operating machinery until you know how it affects you.
Always follow your doctor’s instructions for taking Lisinopril. It is usually taken once daily, with or without food. Remember to take it at the same time each day to maintain a consistent level of the medication in your body. Do not stop taking Lisinopril without consulting your doctor, as sudden discontinuation can cause a rapid increase in blood pressure.
If you experience any side effects while taking Lisinopril, such as a persistent dry cough, swelling of the face, lips, or throat, difficulty breathing, or chest pain, seek immediate medical attention. Your doctor may need to adjust your dosage or switch you to a different medication.
Ask your doctor about Lisinopril today and take control of your blood pressure and heart health. With proper use, Lisinopril can help you live a healthier life.
What is Lisinopril?
Lisinopril is a medication that belongs to a group of drugs called angiotensin-converting enzyme (ACE) inhibitors. It is commonly used to treat high blood pressure (hypertension) and heart failure.
Lisinopril works by relaxing the blood vessels, which helps to lower blood pressure and improve blood flow. It inhibits the enzyme that converts angiotensin I to angiotensin II, a substance that narrows the blood vessels and increases blood pressure. By blocking this enzyme, Lisinopril helps to reduce blood pressure and improve heart function.
In addition to its use in treating hypertension and heart failure, Lisinopril may also be prescribed to prevent kidney problems in people with diabetes, reduce the risk of heart attacks and strokes, and relieve symptoms of certain heart conditions.
This medication is available in tablet form and is generally taken once a day. The dosage may vary depending on the condition being treated and the individual’s response to the medication. It is important to follow the dosage instructions provided by your healthcare provider.
Common side effects of Lisinopril may include dizziness, headache, tiredness, cough, and gastrointestinal symptoms. It is important to notify your doctor if you experience any unusual or severe side effects while taking Lisinopril.
Overall, Lisinopril is an effective medication for managing hypertension and heart failure, and it is commonly prescribed by doctors worldwide.
How does Lisinopril work?
Lisinopril is a medication that belongs to a class of drugs called ACE inhibitors. ACE inhibitors work by blocking the production of a hormone called angiotensin II. This hormone usually causes blood vessels to narrow, leading to an increase in blood pressure. By blocking the production of angiotensin II, lisinopril helps to relax and widen blood vessels, which in turn helps to lower blood pressure.
In addition to lowering blood pressure, lisinopril also helps to reduce the workload on the heart. When blood pressure is high, the heart has to work harder to pump blood throughout the body. By lowering blood pressure, lisinopril helps to reduce the strain on the heart, improving its efficiency and reducing the risk of complications.
Lisinopril is also believed to have other beneficial effects on the body. It is thought to help improve blood flow to the kidneys, which can be beneficial for people with certain kidney conditions. Additionally, it may have anti-inflammatory and antioxidant properties, which could potentially help protect against heart disease and other conditions.
How to take Lisinopril?
Lisinopril is usually taken once daily, with or without food. It is important to take lisinopril exactly as prescribed by your doctor. Do not increase or decrease the dose without consulting your healthcare provider. It may take several weeks for lisinopril to reach its full effect.
Possible side effects
Like any medication, lisinopril can cause side effects. Common side effects may include dizziness, headache, cough, nausea, or fatigue. If you experience any severe or persistent side effects, contact your healthcare provider immediately.
Precautions
Before taking lisinopril, inform your doctor about any other medications you are taking, including over-the-counter drugs and supplements. Lisinopril may interact with certain medications, so it is important to discuss any potential interactions with your healthcare provider.
It is also important to let your doctor know if you have any pre-existing medical conditions, such as kidney disease, liver disease, or diabetes. Lisinopril may not be suitable for everyone, and your doctor will need to evaluate your individual situation to determine if lisinopril is the right medication for you.
| Brand name | Dosage forms | Strengths |
|---|---|---|
| Lisinopril | Tablet | 2.5 mg, 5 mg, 10 mg, 20 mg, 30 mg, 40 mg |
Always consult your doctor or pharmacist for more information about lisinopril and its specific uses and dosages.
Product Label
Indications for use:
- Treatment of hypertension in adults and pediatric patients 6 years and older
- Reduction of mortality in patients with congestive heart failure after myocardial infarction
- Preservation of kidney function in patients with diabetes and hypertension
- Treatment of heart failure
Important Safety Information:
- Lisinopril should not be used during pregnancy
- Do not use Lisinopril if you have a history of angioedema
- Avoid Lisinopril if you have a history of allergic reactions to other ACE inhibitors
Dosage and Administration:
- For hypertension: start with 10 mg once daily, increase to a maximum of 80 mg once daily as needed
- For heart failure or post-myocardial infarction: start with 5 mg once daily, increase to a target dose of 20 mg once daily
- For preservation of kidney function: start with 10 mg once daily, increase to a maximum of 20 mg once daily
Adverse Reactions:
Common adverse reactions to Lisinopril include dizziness, headache, fatigue, cough, and hypotension. Less common adverse reactions may include angioedema, rash, and renal impairment.
Indications
Lisinopril is indicated for the treatment of hypertension (high blood pressure) in adults and pediatric patients 6 years of age and older to lower blood pressure. It may be used alone or in combination with other antihypertensive agents.
Lisinopril is also indicated for the treatment of heart failure (symptomatic or asymptomatic left ventricular dysfunction) in adults, in conjunction with diuretics and, where appropriate, digitalis and/or beta-blockers.
In addition, Lisinopril is indicated in the reduction of risk of myocardial infarction (heart attack), stroke, and death from cardiovascular causes in patients who are at high risk for cardiovascular events.
Lisinopril may be used as part of a combination therapy with other agents, such as aspirin, to reduce the risk of cardiovascular events in patients unable to tolerate ACE inhibitors, or to achieve additional blood pressure control.
Hypertension:
Lisinopril is indicated for the management of hypertension to lower blood pressure. It may be used alone or in combination with other antihypertensive agents. Lisinopril may be used as the initial therapy for the treatment of hypertension in patients likely to respond to therapy with a single drug. In patients who are currently being treated with a diuretic, symptomatic hypotension may occur following the initial dose of Lisinopril. The diuretic should be discontinued, if possible, for 2-3 days prior to initiating therapy with Lisinopril to reduce the likelihood of hypotension.
If blood pressure is not controlled with Lisinopril alone, a diuretic may be added. Lisinopril may be used concomitantly with calcium channel blockers, alpha-blockers, and/or alpha-beta blockers.
Heart Failure:
Lisinopril is indicated for the treatment of symptomatic heart failure in patients with a left ventricular ejection fraction ≤ 35% as adjunctive therapy to diuretics and, where appropriate, digitalis and/or beta-blockers.
Lisinopril has been shown to reduce the risk of hospitalization and death, either alone or in combination with other heart failure therapies, in patients with symptomatic heart failure.
Myocardial Infarction:
Lisinopril is indicated to reduce the risk of death or nonfatal myocardial infarction in patients with a stable coronary artery disease and a high risk of cardiovascular events. Lisinopril can be initiated as early as three days after the myocardial infarction.
Lisinopril can be started with a 5 mg dose, followed by 5 mg after 24 hours, 10 mg after 48 hours, and then 10 mg once daily thereafter. Consideration should be given to administering Lisinopril under close medical supervision, such as in a hospital, for at least two hours following the initiation of therapy or until blood pressure has stabilized.
For patients who develop symptoms of heart failure or are at the risk of developing heart failure after a myocardial infarction, Lisinopril can be initiated at a starting dose of 2.5 mg once daily, under close medical supervision, with subsequent titration to a target dose of 5 mg once daily, as tolerated.
Patients should be titrated to an appropriate dose of Lisinopril, considering baseline blood pressure, kidney function, and other patient-specific factors.
Contraindications
Lisinopril is contraindicated in patients who are hypersensitive to this drug or any other ACE inhibitor. It should not be used in patients with a history of angioedema related to previous treatment with an ACE inhibitor or in patients with hereditary/idiopathic angioedema. Lisinopril is also contraindicated in patients who have experienced angioedema during treatment with any other drugs that inhibit ACE activity.
Patients with a history of bilateral renal artery stenosis or stenosis of the artery to a solitary kidney should not receive Lisinopril, as it may cause renal failure. It is contraindicated in patients with a serum potassium concentration greater than 5.5 mEq/L at the start of treatment.
Pregnant patients should not use Lisinopril, as it can cause injury or death to the developing fetus. It is also contraindicated in breastfeeding women, as Lisinopril has been shown to pass into human milk.
Use in Geriatric Patients
Despite not being specifically contraindicated, it is recommended to use caution when prescribing Lisinopril to geriatric patients. This is due to the higher incidence of renal impairment in this population, as well as the increased risk of hypotension and hyperkalemia.
Use in Pediatric Patients
Lisinopril is not recommended for use in pediatric patients below the age of 6, as its safety and effectiveness have not been established in this population.
Overall, healthcare professionals should carefully evaluate the potential contraindications and assess the benefit-risk ratio before prescribing Lisinopril to patients.
Product Information
In this section, you will find important information about Lisinopril’s product usage and administration. It is essential to follow the instructions provided by your healthcare professional or as indicated on the product label.
Dosage and Administration
| Formulation | Dosage | Frequency | Administration |
|---|---|---|---|
| Lisinopril Tablet | Adults: | Usually 10 mg once daily | Or as prescribed by your healthcare professional |
| Children weighing 20 to 50 kg: | 2.5 to 5 mg once daily | ||
| Children weighing less than 20 kg: | Not recommended |
It is important to take Lisinopril exactly as prescribed by your healthcare professional. Do not exceed the recommended dosage or change the dosage without consulting your doctor.
Lisinopril tablets should be taken orally, with or without food, as directed by your healthcare professional. Swallow the tablets whole with a full glass of water. Do not crush or chew the tablets.
If you miss a dose of Lisinopril, take it as soon as you remember. However, if it is close to the time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one.
For more detailed information on the dosage and administration of Lisinopril, please refer to the product label or consult your healthcare professional.
Dosage and Administration
Proper dosage and administration of Lisinopril are essential for safe and effective use of this medication. It is crucial to carefully follow the directions provided below:
Dosage
The dosage of Lisinopril may vary depending on the individual’s needs and the condition being treated. It is important to consult a healthcare professional to determine the appropriate dosage for you.
Administration
Lisinopril is usually taken orally with or without food, as directed by your healthcare provider. It is recommended to swallow the tablet whole with a full glass of water. Do not crush or chew the tablet.
| Strength | Usual Adult Dose |
|---|---|
| Starting dose | 10-20 mg once daily |
| Maintenance dose | 20-40 mg once daily |
| Maximum dose | 80 mg once daily |
The dosage may be adjusted based on the individual’s response to the medication and their medical condition. It is important to take Lisinopril regularly and at the same time each day to maximize its effectiveness.
If you miss a dose, take it as soon as you remember. However, if it is close to the time for your next scheduled dose, skip the missed dose and resume your regular dosing schedule. Do not take a double dose to make up for a missed one.
It is essential to continue taking Lisinopril even if you feel well. Stopping the medication suddenly can worsen your condition.
If you have any questions or concerns about the dosage or administration of Lisinopril, consult your healthcare provider for further guidance.
Adverse Reactions
When taking Lisinopril, it is important to be aware of the potential adverse reactions that may occur. These can vary from person to person and it is essential to consult with a healthcare professional if any of these reactions occur:
Common Side Effects
Common side effects of Lisinopril include dizziness, headache, cough, fatigue, and nausea. These side effects are generally mild and may diminish or disappear over time. However, if they persist or worsen, it is advisable to seek medical attention.
Severe Side Effects
Although rare, severe side effects can occur while taking Lisinopril. It is crucial to recognize these and seek immediate medical attention if any of the following symptoms are experienced:
- Allergic reactions: These may include swelling of the face, lips, throat, or tongue, difficulty breathing, or hives. Allergic reactions can be life-threatening and require immediate medical attention.
- Chest pain or tightness: This can be a sign of a more serious condition and should not be ignored.
- Fainting: If you experience fainting or lightheadedness, it could be a sign of low blood pressure and should be evaluated by a healthcare professional.
- Irregular heartbeat: If you notice an irregular heartbeat or any changes in heart rate, it is important to seek medical advice.
- Swelling: Lisinopril can sometimes cause swelling of the hands, feet, or ankles. If this swelling is severe or accompanied by other symptoms, medical attention should be sought.
It is important to note that this is not an exhaustive list of adverse reactions associated with Lisinopril. If you experience any unusual or concerning symptoms while taking this medication, it is always best to consult with a healthcare professional for proper evaluation and guidance.